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BioFrontiers is looking for new interdisciplinary faculty members

Through a partnership between the BioFrontiers Institute and the College of Engineering's Department of Computer Science, we are recruiting multiple faculty members at the assistant, associate and full professor ranks for tenure track positions in computational biology. Read more

Loren Hough

Scientist develops a new way to look at a cellular shapeshifter

Tubulin, a protein found in your cells, quietly lends itself to many life processes. It sorts itself into long chains, forming tubes that provide scaffolding for living cells. A versatile shapeshifter, tubulin can arrange itself into different structures during different types of cell behavior. Tubulin gained prominence for medical applications when Taxol, a chemical first found in the bark of the Pacific Yew tree, was developed as a treatment for ovarian, breast and lung cancers. Taxol binds to tubulin and makes it hard for the tubes to grow and shrink, preventing cancer cells from proliferating. “Tubulin is one molecule that does many things in cells,” says Assistant Professor of Physics, Loren Hough, a member of the BioFrontiers Institute. “We're trying to understand how tubulin can play so many different roles."

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Joel Kralj in lab

Innovator Award winner brings the light the electrical changes in cells

Electric voltage powers life: Our brains use electrical transients to process every thought and every heartbeat arises from voltage changes in heart cells.  Due to the small size and fragile nature of cells, it has been technically impossible to measure voltage in neurons in a high throughput manner. Joel Kralj developed a protein based sensor that converts changes in voltage to changes in fluorescence, finally bringing to light the electrical changes in cells. Read more

 

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$1.1 million grant funds CU Boulder research into next-generation vaccines

The University of Colorado Boulder has received a $1.1 million grant from the Bill & Melinda Gates Foundation to develop next-generation vaccines that require no refrigeration and defend against infectious diseases with just one shot. If successful, those advancements could radically transform the difficult task of dispensing life-saving immunizations in developing countries — and improve convenience in every part of the world.

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