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2014

Optimized deep-brain imaging of activity in over a hundred neurons for imaging seizures
Gibson, Emily (PI)
Department of Bioengineering, University of Colorado, Denver, Anschutz Medical Campus
Gopinath, Juliet (Co-PI)
Department of Electrical, Computer and Energy Engineering, University of Colorado, Boulder
Bright, Victor (Co-PI)
Department of Mechanical Engineering, University of Colorado, Boulder
Developing a Platform for in vivo Imaging of Chronic Bacterial Infection
Detweiler, Corrella (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
Palmer, Amy (Co-PI)
BioFrontiers Institute and Department of Chemistry and Biochemistry, University of Colorado, Boulder
 
Single-molecule physical probing of glycan recognition by viral capsid proteins
Garcea, Robert (PI)
BioFrontiers Institute and Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
Perkins, Thomas (Co-PI)
JILA, NIST, Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
 
Conformational dynamics of dystrophin probed using single-molecule FRET
Mallela, Krishna (PI)
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Denver, Anschutz Medical Campus
Nesbitt, David (Co-PI)
JILA, NIST Quantum Physics Division, Department of Chemistry and Biochemistry, University of Colorado, Boulder
 
Extracting diagnostic signals from human microbiome data
Clauset, Aaron (PI)
BioFrontiers Institute and Department of Computer Science, University of Colorado, Boulder
Krauter, Ken (Co-PI)
Institute for Behavioral Genetics and Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
McQueen, Matt (Co-PI)
Institute for Behavioral Genetics and Department of Integrative Physiology, University of Colorado, Boulder
 
The Nano Rainbow: Multicolor Biolabels for Simultaneous Molecular Scale Tracking and Tailored Assays of Biological Agents
Tvrdy, Kevin (PI)
Department of Chemistry and Biochemistry, University of Colorado, Colorado Springs
Pinchuk, Anatoliy (Co-PI)
BioFrontiers Center and Department of Physics and Energy Science, University of Colorado, Colorado Springs
 
Targeted Delivery of Antioxidant Peptides to the Pulmonary Arteries for the Treatment of Pulmonary Hypertension
Villegas, Leah (PI)
Department of Pediatrics/Cardiovascular Pulmonary Research, University of Colorado, Denver, Anschutz Medical Campus
Le, MyPhuong (Co-PI)
Department of Renal Medicine, University of Colorado, Denver, Anschutz Medical Campus
 

2014 Seed Grants for Graduate Students and Postdoctoral Fellows

Analyzing polyomavirus factories with double-helix super resolution microscopy
Heiser, Katie (Lead)
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
Barsic, Anthony (Collaborator)
Department of Electrical, Computer, and Energy Engineering, University of Colorado, Boulder
Dean, Kevin (Collaborator)
BioFrontiers Advanced Imaging Resource, University of Colorado, Boulder
 
Characterizing structural variants in a mouse model of alcohol dependence
Halper-Stromberg, Eitan (Lead)
Department of Computational Biosciences, University of Colorado, Denver
Odell, Aaron (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
 
Non-invasive monitoring of MMP activity of cardiac fibroblasts cultured under diseased and fibrotic microenvironment
Leight, Jennifer (Lead)
Department of Chemical and Biological Engineering, University of Colorado, Boulder
Wan, William (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder
 

2012

Investigating phospholipid asymmetry with specific peptide probes
Xue, Ding (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Yin, Hang (Co-PI)
Biofrontiers Institute, Department of Chemistry and Biochemistry, University of Colorado Boulder
Discovery of novel therapeutics for heart failure by high throughput phenotypic screening
McKinsey, Timothy (PI)
Division of Cardiology/Department of Medicine, University of Colorado Denver
Reid, Brian (Co-PI)
Department of Pharmaceutical Sciences, University of Colorado Denver
Biological applications of novel shape-persistent, three-dimensional organic molecular cages
Liu, Xuedong (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Zhang, Wei (Co-PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Structural studies of DUF1220 protein domains
Sikela, James (PI)
Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine
Pardi, Arthur (Co-PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Chemical synthesis and biological characterization of homogeneous human precursor IL-1α glycoforms
Tan, Zhongping (PI)
Biofrontiers Institute, Department of Chemistry and Biochemistry, University of Colorado Boulder
Dinarello, Charles (Co-PI)
Department of Medicine and Immunology, University of Colorado School of Medicine
Role of the Sf3a mRNA splicing complex in innate immunity regulation
Alper, Scott (PI)
Integrated Department of Immunology, National Jewish Health
Leach, Sonia (Co-PI)
Center for Genes, Environment and Health, National Jewish Health
Blumenthal, Thomas (Co-PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Revolutionizing the way we look at cells: Defining novel organelles by harnessing the power of proteomics and live cell imaging
Ahn, Natalie (PI)
Biofrontiers Institute, Department of Chemistry and Biochemistry, University of Colorado Boulder
Palmer, Amy (Co-PI)
Biofrontiers Institute, Department of Chemistry and Biochemistry, University of Colorado Boulder
4-dimensional flow cardiac MRI for diagnosis of pulmonary hypertension
Fenster, Brett (PI)
Division of Cardiology, National Jewish Health
Hertzberg, Jean (Co-PI)
Department of Mechanical Engineering, University of Colorado Boulder
Schroeder, Joyce (Co-PI)
Department of Radiology, University of Colorado School of Medicine
Cardiac cell mechanobiology
Leinwand, Leslie (PI)
Biofrontiers Institute, Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Anseth, Kristi (Co-PI)
Biofrontiers Institute, Department of Chemical and Biological Engineering, University of Colorado Boulder

Elliman Family Award in Collaborative Stem Cell Research

Treatment of Lipoprotein Lipase (LPL) deficiency with induced pluripotent stem cell (iPSC) technology
Eckel, Robert (PI)
Division of Endocrinology, Metabolism and Diabetes; Division of Cardiology; Department of Medicine; Colorado Clinical and Translational Sciences Institute, University of Colorado Anschutz Medical Campus
Olwin, Bradley (Co-PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Chen, Jiang (Co-PI)
Department of Dermatology, Charles C. Gates Center for Regenerative Medicine and Stem Cell Biology, University of Colorado Anschutz Medical Campus
Wang, Hong (Co-PI)
Division of Endocrinology, Metabolism and Diabetes, University of Colorado Anschutz Medical Campus

2009

Identification of Mammalian Genes Promoting Health Extension
Chick, Wallace (PI)
University of Colorado Denver, Anschutz
Johnson, Thomas (Collaborator)
Institute For Behavioral Genetics, University of Colorado Boulder
p53 meets genomics: elucidating the p53 transcriptome by global run-on deep sequencing
Espinosa, Joaquin (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Robin Dowell (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Proteomic Indicators for Mechanical Property Changes in the Pregnant Cervix
Virginia Ferguson (PI)
Department of Mechanical Engineering University of Colorado Boulder
Jim McManaman (Collaborator)
Department of Physics and Biophysics; Department of OB/GYN, University of Colorado Denver
Antonio Barbera (Collaborator)
University of Colorado Denver, Anschutz
Karen Johscher (Collaborator)
Department of Anesthesiology, University of Colorado Denver
Promoting Purified Dopamine Cell Survival after Transplant using Hydrogel Matrix
Curt Freed (PI)
Clinical Pharmacology, University of Colorado, Denver
Kristi Anseth (Collaborator)
Department of Chemical and Biological Engineering, University of Colorado Boulder
Genome-scale mapping of DNA topology in budding yeast
Jay Hesselberth (PI)
Department of Biochemistry & Molecular Genetics, University of Colorado Denver
Jessica Tyler (Collaborator)
Department of Biochemistry & Molecular Genetics, University of Colorado Denver
Genetics of Gene Expression in COPD
Katerina Kechris-Mays (PI)
Department of Biostatics and Informatics, University of Colorado Denver
Russell Bowler (Collaborator)
Department of Medicine, National Jewish Hospital
Christopher Coldren (Collaborator)
University of Colorado Denver, Anschutz
Structure-function analysis of N-terminal actin binding domain of dystrophin
Krishna Mallela (PI)
Department of Pharma Sciences, University of Colorado Denver
Deborah Wuttke (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Real Time Tracking of Human Papillomavirus Genome Entry and Replication Using Fluorescent Nucleotide Analogues
Dohun Pyeon (PI)
Department of Microbiology and Infectious Diseases, University of Colorado Denver
Robert Kuchta (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Bigger Bang for the Next-Generation-Sequencing Buck: Clear and Present
Ravinder Singh (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Pei-Wen Chiang (Collaborator)
Department of Pediatrics/DNA Diagnostics Lab, University of Colorado Denver
A Chemical Genetics Approach to Study Epigenetic Regulation in Mammalian Skin
Rui Yi (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Xiang Wang (Collaborator)

Department of Chemistry and Biochemistry, University of Colorado Boulder

2007

Genetically Encodable Nanoparticle Tags for Proteome Visualization
Feldheim, Dan (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Eaton, Bruce (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Novel High-throughput cell sorter based on mechanical deformability
Jimenez, Ralph (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Tan, Wei (Collaborator)
Department of Mechanical Engineering, University of Colorado Boulder and UCHSC Cardiology
Calcium Sensors-Probes to Elucidate Mechanisms of Neurodegeneration
Jones, Kevin (PI)
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder
Palmer, Amy (Collaborator)
Departments of Chemistry and Biochemistry, University of Colorado Boulder
Impact of Microbial Ecology on Human Staphylococcus aureus Carriage
Pace, Norman (PI)
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder
Frank, Daniel (Collaborator)
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder
Bessesen, Mary (Collaborator)
Department of Veterans Affairs Medical Center, University of Colorado Denver and Health Sciences Center
Kittelson, John (Collaborator)
Department of Preventive Medicine and Biometrics, University of Colorado Denver and Health Sciences Center
Price, Connie (Collaborator)
Denver Health Medical Center, University of Colorado Denver and UCHSC
Imaging microtubules with an ultra-stable atomic force microscope
Perkins, Thomas (PI)
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder
Hoenger, Andreas (Collaborator)
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Denver Health Sciences Center
Transforming Clinical Pain Control by Targeting a Novel Non-Neuronal Receptor
Sammakia, Tarek (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Watkins, Linda (Collaborator)
Department of Psychology and the Center for Neuroscience, University of Colorado Boulder
Inhalable Antibiotics for the Treatment of Drug Resistant Tuberculosis
Sievers, Robert (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Kisich, Kevin (Collaborator)
Department of Pediatrics, National Jewish Medical and Research Center, University of Colorado Denver
Gene Copy Number Variation in Human Cognitive Disease
Sikela, James (PI)
Department of Pharmacology, University of Colorado Denver Health Sciences Center
Taylor Matthew (Collaborator)
Department of Medicine, Adult Medical Genetics Program, University of Colorado Denver Health Sciences Center
Fingerlin, Tasha (Collaborator)
Department of Preventive Medicine and Biometrics, University of Colorado Denver School of Medicine
Magnetic UV-active nanocomposite particles for advanced in vivo tumor suppression
Weimer, Alan (PI)
Department of Chemical and Biological Engineering, University of Colorado Boulder
Holt, Jeffrey (Collaborator)

Department of Pathology, University of Colorado Denver

2005

Identifying Secreted Bacterial Proteins that Act on Host Cells with Bioinformatics and Genetics
Betterton, Meredith (PI)
Department of Applied Mathematics, University of Colorado Boulder
Detweiler, Corrella (Collaborator)
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder
Knight, Rob (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Altered Protein Phosphorylation in a Mouse Model of Down Syndrome
Cios, Krzysztof (PI)
Department of Computer Science and Engineering, University of Colorado Denver Health Sciences Center
Resing, Katheryn (Collaborator)
Chemistry Department Mass Spectrometry Facility, University of Colorado
Gardiner, Kathleen (Collaborator)
Eleanor Roosevelt Institute, University of Denver
Towards the Rational Development of More Efficient Vaccines
Jones, LaToya (PI)
Department of Pharmaceutical Sciences, University of Denver Health Sciences Center
Wuttke, Deborah (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Using Immerse Virtual Reality for Visualization of the Male Pelvis and Prostate Gland
La Rosa, Francisco (PI)
Department of Pathology, Prostate Diagnostic Laboratory, University of Colorado Health Sciences Center
Spritzer, Victor (Collaborator)
Center for Human Simulation, University of Colorado Health Sciences Center
Dubin, Mark (Collaborator)
BP Center for Visualization, University of Colorado Boulder
Analyses of Genes Associated with Endurance Performance
Mitton, Jeff (PI)
Department of Ecology and Evolutionary Biology, University of Colorado Boulder
Roach, Robert C. (Collaborator)
Colorado Center for Altitude Medicine and Physiology, University of Colorado Health Sciences Center, Denver
Integrating Streptococcus pneumoniae genomic data and human clinical data
Moine, Pierre (PI)
Department of Anesthesiology, University of Colorado HSC, Denver
Serkova, Natalie (Collaborator)
Department of Anesthesiology, University of Colorado Health Sciences Center, Denver
Sain, Stephan (Collaborator)
Department of Mathematics, University of Colorado Denver
Role of Bacterial Infection in the Onset and Progression of Prostatic Diseases
Nash, S. Russell (PI)
Department of Pathology, University of Colorado Health Sciences Center
Pace, Norman (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Detecting Malignant Melanoma with Nanoprobes
Park, Wounjhang (PI)
Department of Electrical and Computer Engineering, University of Colorado Boulder
Bemis, Lynne T (Collaborator)
Department of Medicine, University of Colorado Health Sciences Center, Denver
Virus Counter for Rapid Baculovirus Titer
Pyati, Radha (PI)
Department of Chemistry, University of Colorado Colorado Springs
Rowlen, Kathy (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Edwards, Dean P. (Collaborator)
Department of Experimental Pathology, University of Colorado Health Sciences Center, Denver
Identification of the extracellular matrix proteomes responsible for breast cancer metastasis and tumor cell dormancy
Schedin, Pepper J. (PI)
Department of Medicine, University of Colorado Denver
Reisdorph, Nichole (Collaborator)
Department of Anesthesiology, University of Colorado Health Sciences Center, Denver
Bendiak, Brad K. (Collaborator)
Department of Cellular and Developmental Biology, University of Colorado Health Sciences Center, Denver
Imaging the Onset of Type I Diabetes Using Molecular Contrast Agents
Stodt, Conrad R. (PI)
Department of Mechanical Engineering, University of Colorado Boulder
Lee, Y.C. (Collaborator)
Department of Mechanical Engineering, University of Colorado Boulder
Shandas, Robin (Collaborator)
Department of Mechanical Engineering, University of Colorado Boulder
Hutton, John (Collaborator)

Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver

2002

A Statistical Analysis of Differential Gene Expression in Cerebral Vascular Malformations
Awad, Issam (PI)
Department of Neurosurgery, University of Colorado Denver Health Sciences Center
Sain, Stephen (Collaborator)
Department of Mathematics, University of Denver
Development of tools for RNA structural genomics
Batey, Robert (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Kieft, Jeff (Collaborator)
Department of Biochemistry and Molecular Genetics, University of Colorado Denver Health Sciences Center
Single molecule studies of transcriptions factors
Betterton, Meredith (PI)
Department of Applied Math, University of Colorado Boulder
Goodrich, James (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado, Boulder
Perkins, Thomas (Collaborator)
Department of Applied Math, University of Colorado Boulder
In Silico Identification of the Genes that are Regulated by the Master Sex-Switch protein Sex-lethal
Boswell, Robert (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Osborne, Richard (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Singh, Ravinder (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Using Immersive Virtual Realty for Visualization of Macromolecules
Dubin, Mark (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Pardi, Arthur (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Linguistic and Genetic Relationships in Northern Cameroon (Central Africa)
Frajzyngier, Zygmunt (PI)
Department of Linguistics, University of Colorado Boulder
Hewitt, John (Collaborator)
Institute for Behavioral Genetics, University of Colorado Boulder
Workshop on Mathematical Modeling of Biological Systems
Mallar, James (PI)
Department of Pharmacology, University of Colorado Denver Health Sciences Center
Briggs, William (Collaborator)
Department of Mathematics, University of Colorado Denver
Tyson, John (Collaborator)
University of Colorado Denver Health Sciences Center
Langan, Thomas (Collaborator)
Department of Pharmacology, University of Colorado Denver Health Sciences Center
Time Series Analysis of Hormone Dependent Phasic Variation in the Endometrium
Neville, Margaret (PI)
Department of Physiology and Biophysics, University of Colorado Denver Health Sciences Center
Billups, Steven (Collaborator), Department of Mathematics, University of Colorado Denver
Molecular Analysis of Microbes in Cystic Fibrosis
Pace, Norm (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Accurso, Frank (Collaborator)
Department of Pediatrics, University of Colorado Denver Health Sciences Center
A Genomics Approach for Tracing the Genetic Basis of Typhoid Fever
Ryan, Gill (PI)
Department of Chemical Engineering, University of Colorado Boulder
Detweiler, Corella (Collaborator)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Identification and Characterization of Human Lineage-specific Genes
Sikela, James (PI)
Department of Pharmacology, University of Colorado Denver Health Sciences Center
McGavran, Loris (Collaborator)
Department of Pharmacology, University of Colorado Denver Health Sciences Center
High-throughput Analysis of Chromosome Number Change in Primary Tumor Samples
Strauss, William (PI)
Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder
Franklin, Wilber (Collaborator)
Department of Pathology, University of Colorado Denver Health Sciences Center
Screening for Therapeutic and Environmental Ligand Binding to the Estrogen Receptor
Wuttke, Deborah (PI)
Department of Chemistry and Biochemistry, University of Colorado Boulder
Randolph, Theodore (Collaborator)
Department of Chemistry and Biochemistry, University of Colorado Boulder